منابع مشابه
the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولThe POLG Gene Polymorphism in Iranian Varicocele-Associated Infertility Patients
Objective(s) Varicocele is associated with impaired testicular function and male infertility, but the molecular mechanisms by which fertility is affected have not been satisfactorily explained. The aim of our study was to investigate whether or not the polymerase gamma (POLG) polymorphism is associated with Iranian varicocele patients. Materials and Methods We determined the POLG CAG repe...
متن کاملCytokine Gene Polymorphism in BCG Lymphadenopathy
Background: Tumor necrosis factor-beta or lymphotoxin-alpha (LT-α), IL-4 and IL-10 are determining factors in immunity against BCG. Allelic polymorphisms in the regulatory regions of their genes affect the rate of cytokine production and therefore, the host’s ability in BCG containment. Objective: To study the prevalence of –590 (C/T) and –592 (C/A) allelic distribution of IL-4 and IL-10 promo...
متن کاملStudy of the association between DRD2 Gene Ser311Cys and GSTM1 Gene polymorphism in Schizophrenia
Introduction: Schizophrenia is a mental disorder affecting 1% of the world's population. Two of genes have been recognized to be involved in development of this disease: DRD2 and GSTM1. Methods: This case-control study included 100 patients suffering from schizophrenia who referred to Yazd Neuropsychiatry Hospital. Also, 100 healthy patients without schizophrenia were selected as the control g...
متن کاملAssociation of rs9122 Polymorphism in the MCC Gene with Increasing the Risk of Gastric Cancer
Abstract Background and Aim: Gastric cancer is one of the most common malignancies in the world. Genetic background is known to be one of the risk factors for gastric cancer. One of the genes that have been shown to be involved in various cancers, including gastric cancer, is the MCC gene. There are many SNPs in the MCC gene in the encoding and regulatory regions, one of which is rs9122, which ...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1990
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/18.19.5921